The causes are both genetic and environmental. In the patient’s I have treated over the years all of them have suffered from environmental causes. For this reason, testing is essential. The testing is personalized and unique teach patient. In some cases, there is mutation of a superoxide dismutase gene (SOD). If there is mutation of this gene there is an excessive number of free radicals with oxidative damage and damage to the nerve. Studies have shown elevated levels of oxidative stress and free radicals within the central nervous system as well as peripherally in all ALS patients.

Other factors include glutamate toxicity, mitochondrial dysfunction, environmental toxins, viral infections, and Lyme infections.

Other factors include glutamate toxicity, cervical disc disease, mitochondrial dysfunction, environmental toxins, viral infections, and Lyme infections. Researchers have also identified the role of heavy metals. Both lead and mercury have been linked to Lou Gehrig’s disease. Exposure to pesticides is another risk factor.