Ozone/ Ultraviolet Therapy
Ozone is a Potent Regulator of the Immune System to Kill Cancer
When the immune system is underactive as in cancer, age, and chronic infections, ozone will stimulate it. This unique ability of ozone stems from its actions on the membranes of white cells which cause them to secrete messengers. Messenger hormones called cytokines. Examples of cytokines are interferons, gamma, and alpha, interleukin-2, and tumor necrosis factor, just to name a few. Many of these cytokines have been commercially produced, and are currently being used in conventional clinical medicine to treat the diseases mentioned above.
Ozone Stimulates Increased Uptake and Utilization of Oxygen to Kill Cancer
It does this by stimulating the formation of the enzymes diphosphoglycerate, superoxide dismutase, catalase, and glutathione peroxidase. Diphosphoglycerate enables the release of oxygen from the hemoglobin molecule so that it can be taken up by the cell. Superoxide dismutase, catalase, and glutathione peroxidase are used by the receptive centers of the cell in the mitochondria where the oxygen is processed through the release of energy.
Virtually all persons with chronic disease have a significant deficiency of these enzymes. Ozone is the most potent inducer of these enzymes that have ever been discovered. Some studies have shown that after being treated with ozone oxygen utilization can be improved as much as 40% in patients with various chronic conditions. Obviously, it is difficult to imagine the body fully recovering from any condition if the cells are not getting and utilizing optimum amount s of oxygen. This is one property that makes ozone therapy so effective in so many conditions.
Ozone Improves Blood Circulation to Kill Cancer
It does this by enhancing what is called rheological properties of blood. This term refers to the flow characteristics of blood as a liquid. This effect enables more of the oxygen carrying hemoglobin to reach the capillaries where ultimately the cells will receive more of the oxygen they required. Many patients with chronic conditions, particularly those associated with inflammation, have severe compromise to circulatory flow associated with abnormal rheological characteristics.
Cancer Cells Die When Exposed to Oxygen
Ozone is a mixture of O2 and 03. The molecule is extremely unstable and very quickly forms ozonizes which can diffuse into all parts of the body including cancer cells. It is widely accepted that cancer cells have low oxygen levels in their tissues.
The link between low oxygen and cancer is clear. In 1931 Dr. Warburg won his first Nobel Prize proving that cancer is caused by a lack of oxygen. Low oxygenation results from a buildup of toxins and carcinogens in and around the cells. In order to survive the low oxygen levels, the cancer cells switch to process called aerobic glycolysis. This is a fermentation process that uses sugar for energy. This is called aerobic glycolysis.
Glucose is a critical nutrient for proliferative cancer cells.
There are proliferative cancer pathways which are activated in your body such as P13K/Akt and c-Mye. These pathways drive changes in cellular metabolism to promote cancer cell migration. There are many other pathways which appear to be influenced and directly correlated with low oxygen levels. As oxygen levels drop cancer grows.
The University of Colorado in Denver recently published article showing that a lack of oxygen in cancer cells leads to growth metastasis. The proteins HIF – 1A (hypoxia Inducible factor) and CD24 have been both implicated in the aggressive characteristics, growth and metastasis of cancers. A new study shows that HIF-1A which is activated in a low oxygen environment drives CD 24 over expression making cancers more aggressive. This study definitively links low oxygen with cancer growth and spread. Interestingly HIF -1 is a type of protein called a transcription factor which can control over 300 genes and proteins. Therefore, oxygen can shut off these bad genes and repair your mitochondria so your body can use oxygen and heal your cancer.
Dr. Dominic D'agostino a professor at the University of South Florida Morsani College of Medicine has found that oxygen has toxic effects on cancer cells.
Researchers at the University of Texas, MD Anderson Cancer Center found that important genes and molecules are decreased when deprived of oxygen, which leads to increased cancer progression in vitro and in vivo.
Low oxygen levels also stimulate genes for angiogenesis which is the formation of new blood vessels around the cancer cells so that they may grow and spread.
Low oxygen also makes tumor cells resistant to treatment. Restoring oxygen makes cancer cells more sensitive to treatment.
By restoring oxygen levels in the cells certain genes causing cancer are down regulated and turned off allowing your body to heal.
Cancers do Not Like Oxygen
A high proportion of cancer cells have low activity of enzyme catalase, which degrades the oxidant chemical hydrogen peroxide (H2O2). This adaptation may be beneficial to the cancer, although oxidant chemicals can be toxic to cells, moderate increases in the oxidant stress aid in the growth and survival of many cancers. However, low catalase makes cancer potentially vulnerable to attack by hydrogen peroxide. Recently, researchers at the National Institute of Health have discovered that high concentrations of vitamin C can react spontaneously with molecular oxygen within tumors to generate large amounts of hydrogen peroxide, which can be lethal to tumor cells who is catalase is low. Such large concentrations can only be achieved by high doses of infusions of vitamin C. Remember oral administration is not effective. Interestingly, the vitamin C is nontoxic to normal healthy tissues because they have ample amounts of catalase activity. I do check blood levels of vitamin C to maintain adequate levels.
Coping with Tumor Hypoxia (Low Oxygen in Cancer Cells)
One way to make chemotherapy more effective is to ensure that cancer cells are adequately oxygenated. Because tumor cells tend to have haphazard blood supplies, some parts of tumors tend to receive relatively low blood flow, and are thus poorly oxygenated. This is call hypoxia. For reasons that are not yet entirely clear, hypoxic cancer cells are often harder to kill with chemotherapy or radiotherapy. So I use several strategies for improving the oxygenation of the tumor.
Prior to the administration of low-dose chemotherapy, according to chemo sensitivity tests, patients are administered ozone-autohemotherapy. I usually use this prior to chemotherapy because the ozone-autohemotherapy, along with ultraviolet blood irradiation (wavelengths A, B and C), have been shown to make the red blood cells more flexible and the blood less viscous. The oxygenated red blood cells surrender oxygen to tissues more readily and also prompts vasodilation by stimulating nitric oxide release by the endothelial lining of the small arteries. In that result, there is more oxygen delivery to the hypoxia tumor regions.
According to a new study from the University of Georgia " Low oxygen levels in cells may be a primary cause of uncontrollable tumor growth in some cancers. The authors' findings run counter to widely accepted beliefs that genetic mutations are responsible for cancer growth. Journal of Molecular Cell Biology,2012.
Recent research has shown that hypoxic tissues have a diminished capacity to produce cyclic GMP. Prior to chemotherapy, I administer high oral doses of the B vitamin biotin. In high concentrations, biotin has been shown to directly stimulate cyclic GMP production, both in tumors and healthy tissues. Ultraviolet Blood Irradiation Consists of exposing a sample of blood to ultraviolet light very briefly. The ultraviolet light has been used as a disinfectant for many years even in the hospital. We now know that there is stimulation to the immune system and various enzyme systems. The beneficial effects are as follows:
- Inactivation of toxins.
- Destruction and inhibition of growth of bacteria, fungus and virus in the blood.
- Increasing the oxygen combining power of the blood and oxygen transportation in the organs.
- Activation of steroid hormones.
- Activation of white blood cells.
- Immune stimulation of cellular and humoral immunity.
- Stimulation of fibrinolysis.
- Decreased viscosity of blood.
- Decreased platelet aggregation.
- Improved micro circulation and oxygenation of tissues.
- Anti-inflammatory effects.
- Resolution of vascular spasms.
I use oxidative therapies in my integrative oncology approach. It is not a cure, but it is a piece of the puzzle to help with your cancer diagnosis. More importantly we do evaluation of your circulating cancer stem cells, chemosensitivity testing, natural substances testing, and immunotherapy testing. We only use low dose, metronomic, genomic, chemotherapy after doing molecular genomic testing.