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Lyme Disease

Lyme disease and Co-infections

Thirty years ago, we had very few laboratories for good Lyme testing. Now the testing has much improved and depending were in the world the patient lives I employ different laboratories. I have seen patients from Lyme all around the world. I feel it is widespread and goes undetected in many patients.

I am a member of ILADS, and I am a Lyme literate doctor. I have been treating patients for Lyme disease for many years and have had great success. In my Lyme patients I also see heavy metals, mold, parasites, toxicities, and viral infections. They must all be treated. Your immunity is of utmost importance in getting back your health. This is treated with intravenous therapy, herbal therapy and depending on the severity of your disease I do use antibiotics on a case by case basis. After treating thousands of patients, I believe that combination therapy works best. I am using SOT therapies from RGCC, which I find it to be greatly effective when used with the other therapies. If you have failed antibiotics, I can help you.

Symptoms of Lyme disease

Lyme disease mimics over 350 different medical conditions including Alzheimer’s disease, Parkinson’s disease, Lou Gehrig’s disease, multiple sclerosis, chronic fatigue syndrome, fibromyalgia, asthma, irritable bowel, rheumatoid arthritis, and chronic pain syndrome, ulcerative colitis, interstitial cystitis, neuropathy and many more.

When I see a patient, who has multiple symptoms I think of Lyme disease. In addition, other tickborne pathogens such as Babesia, Bartonella and Ehrlichia are transmitted principally through the bite of a tick. We now know that horseflies, dear flies, mosquitoes, and even spiders can carry this infection. Other modes of transmission include through the placenta from the mother to the baby, breast milk and sexual transmission.

Inflammation causes most of the symptoms:the cytokine Cascade

If you can lower the inflammation in the body, you can become symptom free even if the microbes are still present. Lyme disease is due to the immune system reaction to microbes and toxins. Most symptoms are caused by the immune system attacking the tissues and places were the microbes hide out. Additionally, there is usually the presence of heavy metals, mold infections, and other viral infections. The Lyme spirochetes invade the skin, heart, brain, blood vessels, lymphatics, muscles, tendons, joints spleen and every organ in the body. They can live for months to years. In all cases I treat the inflammatory cytokine Cascade.

Microbial biofilms and resistance

In a study published in the Frontiers in Neurology “The emerging role of microbial biofilms in Lyme neuro-borreliosis,” they state that the presence of biofilm may explain the low rate of Lyme detection in the blood of patients that are infected. The reoccurrence of Lyme and the ability to tolerate multiple cycles of antibiotic treatment is caused by the biofilm. This biofilm is a protective structure for Lyme. Several studies have now shown that the Lyme can switch from a motile to a stationary status in which the cells are embedded in the biofilm and escape from detection of the immune system. The biofilm needs to be broken down and specific therapies are instituted to facilitate this.

These infections are persister infections and need to be treated. Unfortunately, the blood cells of the arteries in the brain can be affected as well as peripheral nerves and joints. At the present time there are probably about 300 different strains of Lyme existing. We still do not know every strain. The problem is that of antibiotic resistance. In addition, when you test some people for Lyme due to a very poor immune response, they do not test positive although they are infected.

Lyme dissemination early and late disease

Early disease at 3-30 days after an infectious tick bite is the time to find it and treat. This phase is curable if treated promptly with oral antibiotics. In the next phase of 1-12 weeks after an infected tick bite there is early dissemination. At this point good response is still seen with antibiotics. Unfortunately, in the late stage more than 3 months after bite there is a complex multisystem multiorgan progressive disabling disease. These are the patients I see in my office. The treatment is multimodal. The main objective is to increase the patient’s immune system. There are immune therapies are instituted as well as SOT from RGCC and other therapies.

Neurologic symptoms

These include problems with sleeping, sensory loss, loss of smell, loss of taste and hearing, visual disturbances, neuropathy, numbness, tingling, burning, crawling, and a stinging sensation. Unfortunately, there is also associated memory loss with diminished visual working verbal memory and processing speed. There is decreased concentration word recall and retrieval. I have seen patients confused and disoriented. Paralysis as seen in Guillain Barre is also seen limb paralysis foot drop mononeuritis multiplex can be seen. I have also seen patients with Alzheimer’s, Parkinson’s, ALS and multiple sclerosis test positive for Lyme disease. Infiltration into the brain is the most dangerous manifestation of Lyme disease, occurring in 10-15% of infected individuals. During the infection them bacteria migrates through the patient altering coagulation and immune response usually reaching the brain within 2 weeks after the bite from the tic.

In some patients anti-microbials and antibiotics are effective but persistent forms of Lyme continue to exist in some patients despite targeted antibiotics. It is thought that these patients have a significant biofilm. This biofilm needs to be broken down along with killing the infection. I have found that SOT therapy from RGCC along with intravenous immune therapies extremely effective. I have also used many natural substances such as herbs and immune enhancers.

Symptoms of mast cell activation

Patients with this syndrome have intent anxiety and depression. They may experience headaches, ringing in the years, sore throats, swollen lymph nodes and indigestion. Unusual neurological symptoms like numbness and tingling in different body parts as well as paralysis and pseudo seizures or possible. The basic principles of treatment are to reduce the production of biochemicals coming from the mast cells. It is important to identify what is triggering the activation in the first place. When the triggers are eliminated the mast cell activation of this appears. In addition, there are many pharmaceutical antihistamines and natural products that are effective.

Hormonal dysregulation

The patients are usually fatigued and exhausted. There is a loss of libido and the patients are very stressed and irritable. Most patients gain weight and when I measure the hormone levels, they are low. Restoration of immunity and hormonal values are necessary.

Neuro-mediated hypotension POTS

The patients usually have a low blood pressure and symptoms of dehydration when lying down or sitting up quickly. There is an autonomic neuropathy usually with pituitary insufficiency. The patients are extremely tired, and they can have rushes or palpitations and need to lay down. The blood pressure will go down upon standing and cause lightheaded and dizzy. As they stand heart rate goes up in compensation. There is a sweating, nausea, vomiting, diarrhea, and esophageal motility problems. I have seen patients have sleep apnea and movement disorders well or sleeping with altered heart rates in arrhythmias.

Why is chronic persistent Lyme so severe infections?

In these patients there appears to be a high spirochete load through either multiple tick bites or long duration that was unrecognized by them. Interestingly many people do not remember a bite or get a rash. After long duration there is a creation of biofilms were protected niches made up of mucopolysaccharides are formed. In addition, there are alternative forms of Lyme such as the cyst form and the L form which cause an additional suppression to the patient’s immune system.

The problem with antibiotics

Published in antimicrobial agents and chemotherapy May 2015 study showed that Lyme can form drug tolerant persister cells. Unfortunately, the cell survives antibiotics because they are dormant. This in addition to the bio films makes antibiotics at this point not effective. Therefore, we are now using pulsing intermittent therapy with a comprehensive natural approach of different herbs and supplements that help break down the biofilm and kill the infections. For this reason, evaluation and the treatment of the patient’s own immune system is exceedingly important. Additionally, supportive oligonucleotide technique (SOT) from RGCC and are used along with intravenous therapies. Natural substances are also ways employed.

Aggravating factors

These include the presence of co-infections such as Bartonella, Ehrlichia, Bartonella along with the various molds, viral infections heavy metals and toxins. I have found by not treating these target aggravating factors it is quite difficult to get the patient better. The 3 most common toxins that contribute to chronic illness appear to be mold, heavy metals especially marked during and pesticides especially glycoside which is found in the herbicide Roundup.

Treatment with natural substances versus antibiotics

Sometimes during treatment, I do use multiple antibiotics which I try to pulse and using lower doses, but I always include natural substances. I believe with an integrative approach is the safe ways of detoxifying the body, killing in the infections, and up regulating the immune system. This is truly personalized medicine and requires any in-depth evaluation of each patient.

Posttreatment Lyme disease syndrome (PTLDS)

We are beginning to see patients that after receiving appropriate antibiotics continue to have symptoms of chronic fatigue, fibromyalgia, headache mental confusion and low-grade fevers. According to the New England Journal of Medicine in March 2016 approximately 20% of people who were treated with antibiotics will have these persistent symptoms. They have both immunosuppression as well as autoimmune disease. This is usually due to persistent infection after antibiotic therapy. The infection becomes resistant.

Bartonella infections

There are many different types of Bartonella species. They are found in dogs, cats, humans, rats, and many other mammals. In a German study with an examination of 270 healthy adults 30% were infected with Bartonella henselae. In a Greece study of 500 healthy adults nearly 35% were shown to be infected with Bartonella. In Spain nearly 30% of 83 cat owners were found to be infected. In Japan 15% of 233 were infected. In Brazil of 437 healthy adults 12% were infected. The same numbers are repeated around the world. Most of my patients also have other infection such as Lyme and co infections. The picture becomes very complex and individualized treatment is indicated in all patients. At times I use multiple laboratories to make the diagnosis.

The most common symptom is lymphadenopathy which is an inflammation of the lymph nodes near the site of the bite or skin break. Bartonella bacteria typically invade parts of the body which include the lymph nodes, spleen, liver, and bone marrow. Other symptoms include fever of unknown origin, liver, and spleen abscesses, retinitis, photophobia, severe fatigue, muscle pain, reactive arthritis, endocarditis, and encephalopathy, headache, memory loss and acute psychiatric symptoms.

The treatment of Bartonella is complex. The cytokine cascade needs to be lowered as well as organ protection and immune enhancement. Depending on where the involvement and symptoms of the patient are, I used different therapies and obviously combine them which I feel is more synergistic.

SOT therapy from RGCC is always employed along with natural substances, herbs, oxidative therapy and at times antibiotics. Immune enhancers are always utilized. I routinely use a multitude of intravenous therapies.

Babesia Infections

These are protozoa and not bacteria acting like malaria. They have been living for 100s of millions a years. As we have destroyed planet, they are now coming to be more prevalent with many species and mutations. The transmission in humans is primarily by a tick bite. In addition, we are seeing infections through transfusions of infected blood increasingly becoming a problem. Placental transfer from an infected mother to an unborn child has also been documented. There are many species that effect humans from all around the world. Most people remain asymptomatic because the immune function is healthy. For others they may merely experience a bout of the “flu” along with fatigue, chills, sweats, headache, anorexia, cough, body aches and nausea.

The treatments are intravenous therapies, organ support and protection and at times antibiotics. There is no one size fits all treatment that works for everyone. Again, immune function is extremely important, and suppression of the cytokine cascade can alleviate symptoms quickly.

SOT therapy from RGCC is effective. In acute infection I believe to antibiotics need to be used. In someone with a splenectomy aggressive therapy needs to be done. The Babesia is harder to kill the malaria because it is slow growing and occurs in low concentrations in the body. The symptoms associated with Babesia infection are related to the clumping of the blood cells in the blockage of the small blood vessels. This process impedes recovery. There is evidence that using an anticoagulant is effective along with the antibiotics and herbs. It does suppress the replication of the organisms. Restoration of immunity is always indicated.

Ehrlichia and Anaplasma infections

These are both transmitted by tics, most commonly hard tics but soft tics and transmission to mammals such as bats has been documented. New research shows that they can also be transmitted by fleas and both organisms are commonly found in cats and dogs when tested.

Ehrlichia can be transmitted by the lone star tick. This ranges from West Central Texas North to Iowa and Eastward to southeastern United States and up to New England. Ehrlichia have also been transmitted through transfusions in organ transplantation. Ehrlichia infections and Anaplasma infections are often asymptomatic or present as a case of “minor flu”. Most infections clear but in patients with low immunity we see another picture. Patients may have fever, headache, low white blood cell count, low platelet count and elevated liver enzymes.

The diagnosis is complex, and treatment depends on the symptoms of the patient and the severity of disease. SOT therapy from RGCC is employed along with immune enhancers, herbs, and various intravenous therapies. Organ support and protection, immune modulation, cytokine disruptors and specific herbs are utilized. If the symptoms are severe antibiotics are used along with natural therapies.

Herbal therapies

It is now possible to evaluate the medicinal benefits of herbs. They have a wide range of effects which include a broad-spectrum of antimicrobial properties. They are active against bacteria, virus, protozoa and harmful fungus and molds. In addition, there are anti-inflammatory and can restore the immune function. They also have an antioxidant ability and have been found to be protective against cancer.

I routinely use them and take them myself. Many different companies offer the various beneficial mixtures. Herbs are synergistic and bacterial resistance is very rare. They are effective.

Supportive oligonucleotide technique (SOT) from RGCC

SOT therapy from RGCC as a treatment uses the messenger RNA to influence the genes in the Lyme or viral infection. I also use them with cancer. The laboratory can identify certain genes in the Lyme organism and viruses and target them to damage and silence those genes effectively killing the organism. This is called anti-sense therapy where there is a creation of up to 1 billion copies of SOT molecules to fight the Lyme or viral infection. This is called gene silencing therapy. I have taken them myself and have found them to be very effective.

Intravenous Therapy for Lyme and co-infections

New intravenous therapies are anti-inflammatory and can up regulate the immune system. They can also repair damaged tissue as seen in Lyme disease. Many patients may experience an improvement of their energy level as well as their weakness and muscle strength. Please call us and asked about details.

Combination therapies work best

Combination synergistic therapies are critical to. Initially diagnosis is done through multiple laboratories. Treatments are aimed at optimizing the patient’s own immune system. The components to overcome your disease include controlling symptoms, suppressing microbes, controlling inflammation, restoring immune function, healing and repair damage, and hormonal balance. I feel a holistic approach to recovery from chronic illness is important.

Treatments are tailored to each patient and are based on the patient’s unique genes and environmental factors. Other factors such as virus, parasites, mold, heavy metals and breaking down the biofilms are of critical importance. Restoration of your microbiology is essential.

Supportive oligonucleotide’s SOT from RGCC, intravenous therapies and herbs are of great value in your treatment plan. If you decide to use synthetic antibiotics, we need the pulse them and use them sparingly. Remember survival strategy used by these microbes make them very often resistant to antibiotic therapy.

Remember that the potential for acute severe illness with these microbes is high, especially with Lyme disease. For this reason, anyone presenting with a history of tick bite, high fever and severe flulike illness should receive at least 30 days of antibiotic therapy I believe that antibiotics should be started empirically without waiting for the test results. Unfortunately, the use of antibiotics long term creates resistance and enhances virulence and nonpathogenic bacteria. Antifungals, antiviral treatment and antiparasitic drugs are utilized in most of my patients. All treatments are personalized.

If you would like more information on Lyme disease, please call us at 480-860-2030.


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