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Dipyridamole for cancer

This is a drug called Persantine which inhibits platelets. It is an old drug with a long history of safety. It is an antiplatelet drug which is a phosphodiesterase inhibitor. It prevents blood clots, strokes, and heart attacks by preventing platelet adhesion activation.

Cancerous cells use platelet-derived growth factors to induce new blood vessel formation a process called angiogenesis. As the new blood vessels grow the tumor also grows. The good news is that this re-purposed cancer drug can decrease platelet release of the platelet-derived growth factors inhibiting new blood vessels around your cancer.

Persantine also has an anti-inflammatory effect, inhibiting Cox 2 inflammatory pathways which are upregulated in cancer cells.

There is also synergy with chemotherapy including vincristine, etoposide, and 5-FU. Dipyridamole also a viral inhibitor of reactivation of herpes simplex, and it prevents Epstein-Barr reactivation. It is also active against influenza and rhinovirus.

If you are interested in re-purposed cancer drugs, evaluation of circulating cancer stem cells, low-dose metronomic genomic chemotherapy, natural substances, and cancer vaccines we can help.

In 2017 the anticancer effect of oral administration was investigated on gastric cancer cell lines using in vitro and in vivo animal models. They found the remarkable inhibition of gastric cancer cell proliferation. There was down regulation of cancer signals.

If you are interested in repurposed cancer drugs, evaluation of circulating cancer stem cells, low dose metronomic genomic chemotherapy, natural substances, and cancer vaccines we can help.

Please call us at 480-361-7020

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