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Beta-blockers as an anticancer drug

Chronic stress with secretion of the stress hormones called catecholamines such as epinephrine and norepinephrine, attach to the receptors in the cancer cells. This stimulates growth, proliferation, and invasion. These catecholamines are deleterious to her immune system, increase our susceptibility to virus and delay wound healing. I believe the chronic stress can aggravate cancer. The good news is that with an old drug called a beta-blocker specifically known as propranolol we can block the stress hormones.

Studies have shown that blocking beta adrenergic receptors with propranolol reduces cancer cell proliferation and migration causing metastasis. There was also improved survival. Propranolol synergizes with conventional chemotherapy.

In 2019 Montoya et al. used propranolol in breast cancer showing reduced tumor proliferation, decreased mortality, decreased metastasis, longer survival, and reduced cancer recurrence. It also has an antiangiogenic effect.

Published in cancer is 2018, Dr. Lucido et al., using head and neck squamous cell cancer showed that a combination of propranolol and dichloroacetate (DCA) resulted in a significant delay in tumor growth with no toxicity and improve sensitivity to chemotherapy and radiation.

He observed that propranolol alone inhibited mitochondrial metabolism with decreased oxygen consumption and glycolytic activity. This glucose dependence was then blocked by dichloroacetate. He concluded to say “this was highly effective therapeutic combination.

Propranolol has been effective in the following cancer cell types: Neuroblastoma, angiosarcoma, breast cancer, melanoma, lung cancer, multiple myeloma, cervical cancer, leukemia, hepatocellular carcinoma, ovarian cancer, prostate cancer, pancreatic cancer, and bone osteosarcoma.

If you are interested in combining re-purposed cancer drugs, low dose metronomic targeted genomic chemotherapy, natural substances, cancer vaccines and other therapies we can. I am a cancer survivor for 20 years

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